KCCI reports a recent Iowa Poll reports a majority of Iowans who would be in favor of legalizing marijuana. The Des Moines Register/Mediacom Iowa Poll was conducted between March 7 and March 10 and 775 Iowans participated. It reports 54% were in favor of legalizing marijuana, 39% were opposed and 6% were unsure. The results were similar to the March 2020 Iowa Poll.

The poll also asked participants about expanding the medical marijuana program in the state. Of the participants, 78% said the program should include more diseases and conditions, 14% opposed the expansion, and 7% were unsure. There was a margin of error of 3.5 percentage points.