DES MOINES, Iowa (AP) — It could be a profitable weekend for lucky lottery players as two of the largest jackpots in U.S. history will be on the line. Numbers will be drawn Friday night for the $750 million Mega Millions prize, the fifth-largest jackpot ever. On Saturday, players will have a chance at a $640 million Powerball prize, the eighth-largest jackpot. The listed jackpot amounts refer to winners who opt for an annuity, paid over 30 years.

A lottery customer purchases lottery tickets at Conjelko’s Dairy Store in Windber, Pa., as the Mega Millions grew to $750 million and the PowerBall to $ 640 Million on Thursday, Jan. 14, 2021. (Todd Berkey/The Tribune-Democrat via AP)

Most winners choose cash prizes, which for Mega Millions would be an estimated $550.6 million. For Powerball it would be $478.7 million. Mega Millions and Powerball are both played in 45 states as well as Washington, D.C., and the U.S. Virgin Islands. Powerball also is offered in Puerto Rico.