Here is the latest Mid-America sports news from The Associated Press

TULSA, Okla. (AP) — Ohio State upset sixth-seeded Iowa State in the opening round of the Midwest Region. The 62-59 victory earned the 11th-seeded Buckeyes a second-round game against Houston. Kaleb Wesson had 21 points and 12 rebounds to lead Ohio State. Keyshawn Woods added 19 points. Iowa State led just once in the second half but had a chance to send the game into overtime when Nick Weiler-Babb missed an open 3.

IOWA CITY, Iowa (AP) — Jordan Roundtree hit a free throw after being fouled with 1.1 seconds left in overtime and seventh-seeded Missouri beat Drake 77-76 to advance to the NCAA Tournament’s round of 32 for the third time in four years. Sophie Cunningham scored 21 points and Cierra Porter had 18 for the Tigers (24-10), who can advance to the Sweet 16 for the first time since 2001 with a win over second-seeded and host Iowa on Sunday.

COLUMBUS, Ohio (AP) — Luka Garza scored 20 points, Jordan Bohannon made a three-point play during Iowa’s closing surge, and the 10th-seeded Hawkeyes rallied for a 79-72 victory over No. 7 Cincinnati. The Big Ten sent eight teams into the field, the most in its history, and won seven of its first eight games, Wisconsin’s loss to Oregon the only blemish in the opening round.

SAN JOSE, Calif. (AP) — Evan Leonard hit back-to-back 3-pointers to start a run of 12 straight points in the second half that sent No. 13 seed UC Irvine to a 70-64 upset over fourth-seeded Kansas State in the first round of the NCAA Tournament. The Anteaters held on after that run and stunned the regular-season co-champions of the Big 12 for the first tournament win in school history.

UNDATED (AP) — A person familiar with the negotiations tells The Associated Press the Cardinals and slugging first baseman Paul Goldschmidt are nearing completion of a $130 million, five-year deal that will make him the highest-paid player in club history. The Cardinals acquired the 31-year-old Goldschmidt in a trade with Arizona. He had just one year left on his contract, though, and his new deal would keep him with St. Louis through 2024.