Here is the latest Mid-America sports news from The Associated Press

KANSAS CITY, Mo. (AP) — Tim Anderson hit a two-run homer in the 12th inning, and the Chicago White Sox beat the Kansas City Royals 4-2. Anderson’s blast off Burch Smith, the sixth Royals pitcher, landed just beyond the fence in left-center. Juan Minaya pitched two scoreless innings for the win. Hector Santiago, the eighth Chicago pitcher, picked up his second save in as many chances. The White Sox snapped a seven-game skid, one game short of their season-worst losing streak.

ST. LOUIS (AP) — Jameson Taillon won his fourth straight start, Jacob Stallings drove in three runs and the Pittsburgh Pirates slowed the Cardinals with a 4-3 victory that stopped the Cardinals’ three-game winning streak. St. Louis entered 34-18 under new manager Mike Shildt and with the most wins in the NL after the All-Star break. The Cardinals’ lead for the second NL wild card was cut to two games over the Los Angeles Dodgers. Taillon allowed two runs and four hits in seven innings, leaving with a 4-1 lead.

KANSAS CITY, Mo. (AP) — By almost any measure, Patrick Mahomes aced his first test as the starting quarterback of the Chiefs. He threw a bunch of TD passes, led Kansas City to a road win against a division foe and, perhaps most importantly, was perfect where it mattered most: turnovers. He didn’t throw an interception in the 38-28 victory.

UNDATED (AP) — Iowa State has found a replacement for its canceled opener. The Cyclones will host Incarnate Word on Dec. 1 unless Iowa State qualifies for the Big 12 title game or Incarnate Word reaches the FCS playoffs. Iowa State will pay Incarnate Word $300,000 for the game and provide use of a charter aircraft. Iowa State and South Dakota State played only a few minutes before their Sept. 1 game was called off because of lightning.