Mayfield threw TD passes to Westbrook and Dimitri Flowers in the final 4:16 of the first half, extending his streak of games with at least four touchdown tosses to an FBS-high four games. Mayfield has 31 scoring passes, good for second nationally, with just six interceptions.

Oklahoma’s defense stiffened after some early struggles, allowing just seven points in the second half. Jacob Park passed for 160 yards and two touchdowns for the Cyclones. They’ve dropped five straight. Iowa State played without rushing leader Mike Warren. He sprained an ankle last week in a loss to Kansas State.

Iowa State next travels to face Kansas in the least appealing matchups in the Big 12 this year. The Jayhawks are 1-7 and have lost their last three games by an average of 40 points