Drake led 38-29 at the half but DePaul chipped away and trailed just 75-73 entering the final minute following a Darrick Wood layup. After a turnover by Drake’s Reed Timmer, Cain hit the game-tying layup and drew the foul on the Bulldogs’ Ore Arogundade. He dispatched the free throw for a 76-75 Blue Demons lead.

Timmer had a final shot to win it for Drake, but his 3-pointer missed at the buzzer. Brandon Cyrus finished with 14 points and eight boards for DePaul. Wood added 12 points. Timmer led Drake (1-6) with 18 points. Billy Wampler had 17 for the Bulldogs, who have lost four consecutive games.